Druggio

Cryopyrin associated periodic syndrome

Cryopyrin associated periodic syndrome (CAPS) all arise from a missense mutation in the CIAS1 gene that encodes NALP3. These are autosomal dominant inherited disease characterized by recurrent inflammatory episodes. The pathogenic mechanism of these syndromes is attributed to increased activation of the NALP3 inflammasome, resulting in aberrantly high production of IL-1beta.

Drugs that treat Cryopyrin associated periodic syndrome

Ilaris

Made by

Novartis

Approval date

2011/9/26

Treats

Tumor necrosis factor receptor-associated periodic syndrome, Familial periodic fever Cryopyrin associated periodic syndrome Mevalonate kinase deficiency Familial Mediterranean fever, Familial hereditary periodic fever syndromes Familial cold autoinflammatory syndrome, Familial cold urticaria See 1 more disease(s)